Eur J Surg Oncol. 2007 Mar 16; [Epub ahead of print]

van der Ploeg IM, van Esser S, van den Bosch MA, Mali WP, van Diest PJ, Borel
Rinkes IH, van Hillegersberg R.
Department of Surgery, University Medical Centre Utrecht, P.O. Box 85500, 3508 GA
Utrecht, The Netherlands.

INTRODUCTION: Radiofrequency ablation (RFA) provides an effective technique for minimally invasive tissue destruction. A novel application is the use for treatment of small breast carcinoma.

METHODS: A broad search was conducted in Pubmed, Embase and the Cochrane library. Results of the relevant articles were analysed.

RESULTS: The analysed studies were all feasibility or pilot studies using different patient and tumour characteristics and ablation settings. Despite many methodological differences, high percentages of complete tumour ablation varying between 80% and 100% were reported.

CONCLUSION: Radiofrequency ablation is a promising new tool for minimally invasive ablation of small carcinomas of the breast. A large randomized control study is required to assess the long-term advantages of RFA compared to the current breast conserving therapies.

PMID: 17369003 [PubMed - as supplied by publisher]